Tumors of the urinary bladder is about 4% of all neoplasms, second in frequency only to tumors of the stomach, esophagus, lung and larynx. According to world statistics, the incidence of this disease increases.

In men, bladder tumor mark much more often than women (4:1). Most tumors of the bladder in men explain the more frequent exposure to carcinogenic substances and more prolonged delay in the urine in the bladder.

Neoplasms of the bladder are found mainly in people older than 50 years. Tumors of the urinary bladder in children are rare - 60 times less frequently than in adults, more frequently in boys. Tumors may be located in all parts of the urinary bladder, but most of their localization, urocystic triangle and its surrounding areas.

At present most widespread chemical theory of the origin of bladder tumors. In the second half of XIX century. Attention was drawn to the frequent occurrence of bladder tumors in workers engaged in the manufacture of aniline dyes. Later it was found that not themselves carcinogenic aromatic amines p-naphthylamine, benzidine), and their final metabolites (substances such ortoaminofenolov) cause the formation of bladder tumors. Then it became clear that a great similarity with derivatives of aromatic amines have some substances that are products of metabolism in the human body, mainly metabolites such ortoaminofenolov (skatole, indole, etc.) that are carcinogenic properties. These endogenous carcinogenic ortoaminofenoly are constantly in the urine of healthy people. In this regard, an important pathogenetic importance stagnation of urine in the bladder. Tumors of the urinary bladder in children are mesenchymal in nature. In their morphological study revealed rhabdomyosarcoma, leiomyosarcoma, miksosarkoma. Very rarely detected fibroids, dermoid, angioma, fibroepiteliomy. Sarcomas differ expressed malignancy.