General information of Ewing's sarcoma
Ewing's sarcoma a cancer affecting the bone and soft tissue okolokostnye, more common in adolescents and young males. It is believed that the pathogenesis of Kaposi's sarcoma is playing the role of chromosome mutation, and factor in the clinical manifestation of tumor is a bone injury. Aggressiveness of tumor depends on the patient's age - from teenagers during more active than adults. The tumor develops as a tube, and in flat bones, and most commonly affects the region - is the major bones of the hip, shoulder, pelvis, as well as the ribs, scapula and vertebrae.

Histologically Ewing's sarcoma is composed of the same type of small cells, which look at the specific color of blue ( «small blue cells»). By the same group include neuroblastoma, lung cancer and lymphoma. Common to all these tumors is that their cells are undifferentiated.

For bone sarcomas is characterized by rapid growth and early metastasis. Ewing's sarcoma is the second most common among malignant bone tumors in children - is 10-15%. This tumor is rare in children younger than 5 years and adults older than 30 years. The peak incidence occurs in 10 -15 years.

The cause of malignant bone tumors is not yet known, but it is proved that in 40% of the occurrence of bone sarcoma provoking trauma.

Ewing's sarcoma is composed of small round cells with scanty cytoplasm, round nucleus containing delicate chromatin and weakly observable basophilic nukleoly. In contrast to osteosarcoma, it does not produce osteoid.

The idea of the endothelial nature of Ewing tumors prevailed before 1980. Studies in recent years, showed neurogenic nature of Ewing tumors. Although most Ewing's sarcoma is an undifferentiated tumor of bone, there is evidence of soft tissue lesions (ekstraossalnaya Ewing's sarcoma). In the literature, the term appeared «family of tumors such as Kaposi's sarcoma